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Aspirin

Aspirin is one of the most used medicines. It has for long been a major analgesic and antipyretic, but now is widely used as an antiplatelet to reduce heart disease and strokes. It may also prevent some forms of cancer. But it is not without harm, notably its effects on the gut, causing bleeding. This resource centre aims to pull together stuff on aspirin.

Analgesia

Aspirin in postoperative pain Aspirin with codeine in postoperative pain Aspirin for acute migraine Aspirin plus metoclopramide for acute migraine Aspirin for dysmenorrhoea

Aspirin and cancer

Aspirin and colorectal adenoma Aspirin/NSAID and oesophageal cancer Aspirin and lung cancer Aspirin and pancreatic cancer Colorectal polyps: aspirin, coxibs, and NSAIDs Low-dose aspirin and cancer

Harm

Aspirin, NSAID, Coxib and PPI Aspirin in low risk individuals Gastrointestinal harm with aspirin Increased risk of intracranial haemorrhage with aspirin plus warfarin Low dose aspirin - harms and benefit Low dose aspirin and haemorrhage in older people More on NSAID adverse effects NSAIDs and adverse effects Preventing GI bleeds with low dose aspirin The price of aspirin The trouble with aspirin What patients think

Protecting against stroke or heart attack

Aspirin in high-risk patients Aspirin or anticoagulant in nonvalvular AF Aspirin, clopidogrel or ticlopidine for stroke prevention? Aspirin for ischaemic stroke Aspirin and stroke Aspirin in low risk individuals Antithrombolytics and stroke in AF Increasing aspirin use for secondary prevention of IHD Low dose aspirin - harms and benefits NNTs for stroke prevention Primary prevention with aspirin Secondary prevention with aspirin Thromboprophylaxis and death after total hip replacement Warfarin or aspirin or both after myocardial infarction

Other actions of aspirin

Aspirin and cataracts Aspirin and postoperative bleeding after CABG Aspirin in pregnancy and congenital abnormalities Aspirin for prevention of preeclampsia in women with abnormal uterine artery doppler Antiphospholipid antibodies and pregnancy loss DVTs and all that Travel and DVT: brief update Perioperative aspirin use? Prevalence of aspirin resistance