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Cernilton for BPH

Clinical bottom line

In small randomised studies lasting 12-24 weeks cernilton provided no evidence of relief of symptoms of benign prostatic hyperplasia. Urinary flow rates, residual volume nor prostate size were better with cernilton.


Cerniltion is prepared from the rye grass pollen Secale cereale.

Reference

R MacDonal et al. A systematic review of Cernilton for the treatment of benign prostatic hyperplasia. BJU International 1999 85: 836-841.

Review

The review had an excellent comprehensive search strategy for randomised trails of cernilton. There was no common outcome measure.

Results

There were four randomised trials of 444 men. Two used a placebo control and two used other complementary therapies.

Cernilton was ineffective.

Comment

There is no evidence that cernilton is of any benefit for men with BPH.