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This month Bandolier returns to the difficult world of readers' questions. There is a big overlap with another world, that of little evidence. So answering readers' questions often means delving into areas where we have to make the best of what we have.

One of these simple questions to which the only answer is long, complicated, and unsatisfactory is that of whether stopping statins is dangerous. Many (most?) people who start statins do eventually stop them, but why on earth should there be any danger? Actually, there is some interesting biology behind possible problems, and at least two bits of evidence hinting that theory and practice are not strangers.

The whole business of pneumococcal vaccination is also a perennial. Most of any possible benefit seems to be in incredibly rare outcomes, where randomised trials or even meta-analysis of randomised trials collect too few events to be sure of the result. Good observational studies coming up with the same answer give us much more confidence.

Subscription renewal

For many Bandolier readers, this July issue will mark the last paper copy they will have under their present subscription arrangement. You should have had a renewal letter, but if you have mislaid it, or forgotten to renew, don't panic.

If you wish to receive a print copy of Bandolier you need to subscribe. You need to download a subscription form (pdf), and then either fax the completed form to us at 01865 226978 or email it as an attachment to Institutions in health services or non-profit organisations around the world will be able to buy in bulk and distribute themselves. Institutions interested in bulk purchase should email or fax an enquiry to 01865 226978.

And the price is the same now as it has been for most of Bandolier's 10 years, despite hikes in paper, postage and printing.

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